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Differential expression of tissue-restricted antigens among mTEC is associated with distinct autoreactive T cell fates
Medullary thymic epithelial cells (mTEC) contribute to the development of T cell tolerance by expressing and presenting tissue-restricted antigens (TRA), so that developing T cells can assess the self-reactivity of their antigen receptors prior to leaving the thymus. mTEC are a heterogeneous populat...
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| Gepubliceerd in: | Nat Commun |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7381629/ https://ncbi.nlm.nih.gov/pubmed/32709894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17544-3 |
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