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Single-cell RNA-sequencing resolves self-antigen expression during mTEC development
The crucial capability of T cells for discrimination between self and non-self peptides is based on negative selection of developing thymocytes by medullary thymic epithelial cells (mTECs). The mTECs purge autoreactive T cells by expression of cell-type specific genes referred to as tissue-restricte...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766627/ https://ncbi.nlm.nih.gov/pubmed/29330484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-19100-4 |
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