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Strength and Numbers: The Role of Affinity and Avidity in the ‘Quality’ of T Cell Tolerance

The ability of T cells to identify foreign antigens and mount an efficient immune response while limiting activation upon recognition of self and self-associated peptides is critical. Multiple tolerance mechanisms work in concert to prevent the generation and activation of self-reactive T cells. T c...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: This, Sébastien, Valbon, Stefanie F., Lebel, Marie-Ève, Melichar, Heather J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234061/
https://ncbi.nlm.nih.gov/pubmed/34204485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061530
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