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The Quest for the Best: How TCR Affinity, Avidity, and Functional Avidity Affect TCR-Engineered T-Cell Antitumor Responses

Over the past decades, adoptive transfer of T cells has revolutionized cancer immunotherapy. In particular, T-cell receptor (TCR) engineering of T cells has marked important milestones in developing more precise and personalized cancer immunotherapies. However, to get the most benefit out of this ap...

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Foilsithe in:Cells
Main Authors: Campillo-Davo, Diana, Flumens, Donovan, Lion, Eva
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408146/
https://ncbi.nlm.nih.gov/pubmed/32708366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071720
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