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Affinity and Avidity in Antibody-Based Tumor Targeting

Many factors contribute to successful tumor targeting by antibodies. Besides properties of the tumor tissue and general antibody pharmacology, a relationship exists between an antibody and its antigen that can shape penetration, catabolism, specificity, and efficacy. The affinity and avidity of the...

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Detalhes bibliográficos
Main Authors: Rudnick, Stephen I., Adams, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902227/
https://ncbi.nlm.nih.gov/pubmed/19409036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2009.0627
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