Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury

In the context of human disease, the mechanisms whereby transcription factors reprogram gene expression in reparative responses to injury are not well understood. We have studied the mechanisms of transcriptional reprogramming in disease using murine kidney podocytes as a model for tissue injury. Po...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Ettou, Sandrine, Jung, Youngsook L., Miyoshi, Tomoya, Jain, Dhawal, Hiratsuka, Ken, Schumacher, Valerie, Taglienti, Mary E., Morizane, Ryuji, Park, Peter J., Kreidberg, Jordan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2020
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380960/
https://ncbi.nlm.nih.gov/pubmed/32754639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb5460
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