Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury

In the context of human disease, the mechanisms whereby transcription factors reprogram gene expression in reparative responses to injury are not well understood. We have studied the mechanisms of transcriptional reprogramming in disease using murine kidney podocytes as a model for tissue injury. Po...

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Publicado en:Sci Adv
Autores principales: Ettou, Sandrine, Jung, Youngsook L., Miyoshi, Tomoya, Jain, Dhawal, Hiratsuka, Ken, Schumacher, Valerie, Taglienti, Mary E., Morizane, Ryuji, Park, Peter J., Kreidberg, Jordan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380960/
https://ncbi.nlm.nih.gov/pubmed/32754639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb5460
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