Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury

In the context of human disease, the mechanisms whereby transcription factors reprogram gene expression in reparative responses to injury are not well understood. We have studied the mechanisms of transcriptional reprogramming in disease using murine kidney podocytes as a model for tissue injury. Po...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Ettou, Sandrine, Jung, Youngsook L., Miyoshi, Tomoya, Jain, Dhawal, Hiratsuka, Ken, Schumacher, Valerie, Taglienti, Mary E., Morizane, Ryuji, Park, Peter J., Kreidberg, Jordan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380960/
https://ncbi.nlm.nih.gov/pubmed/32754639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb5460
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