Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury

In the context of human disease, the mechanisms whereby transcription factors reprogram gene expression in reparative responses to injury are not well understood. We have studied the mechanisms of transcriptional reprogramming in disease using murine kidney podocytes as a model for tissue injury. Po...

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Publicat a:Sci Adv
Autors principals: Ettou, Sandrine, Jung, Youngsook L., Miyoshi, Tomoya, Jain, Dhawal, Hiratsuka, Ken, Schumacher, Valerie, Taglienti, Mary E., Morizane, Ryuji, Park, Peter J., Kreidberg, Jordan A.
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380960/
https://ncbi.nlm.nih.gov/pubmed/32754639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb5460
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