A Mammal-Specific Exon of WT1 Is Not Required for Development or Fertility

The WT1 tumor suppressor gene is a zinc finger-containing transcription factor which is required for development of the kidney and gonads. A mammal-specific alternative splicing event within this gene results in the presence or absence of a 17-amino-acid sequence within the WT1 protein. To determine...

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Detalhes bibliográficos
Main Authors: Natoli, Thomas A., McDonald, Alice, Alberta, Julia A., Taglienti, Mary E., Housman, David E., Kreidberg, Jordan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133868/
https://ncbi.nlm.nih.gov/pubmed/12024052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4433-4438.2002
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