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Expression of inhibitory receptors by B cells in chronic human infectious diseases restricts responses to membrane-associated antigens

Chronic human infectious diseases, including malaria, are associated with a large expansion of a phenotypically and transcriptionally distinct subpopulation of B cells distinguished by their high expression of a variety of inhibitory receptors including FcγRIIB. Because these B cells, termed atypica...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Ambegaonkar, Abhijit A., Kwak, Kihyuck, Sohn, Haewon, Manzella-Lapeira, Javier, Brzostowski, Joseph, Pierce, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380957/
https://ncbi.nlm.nih.gov/pubmed/32754637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba6493
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