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RocA Regulates Phosphatase Activity of Virulence Sensor CovS of Group A Streptococcus in Growth Phase- and pH-Dependent Manners

The control of the virulence response regulator and sensor (CovR-CovS) two-component regulatory system in group A Streptococcus (GAS) strains regulates more than 15% of gene expression and has critical roles in invasive GAS infection. The membrane-embedded CovS has kinase and phosphatase activities,...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Chiang-Ni, Chuan, Chiou, He-Jing, Tseng, Huei-Chuan, Hsu, Chih-Yun, Chiu, Cheng-Hsun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380576/
https://ncbi.nlm.nih.gov/pubmed/32434842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00361-20
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