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Cytotoxicity and Survival Fitness of Invasive covS Mutant of Group A Streptococcus in Phagocytic Cells

Group A streptococci (GAS) with spontaneous mutations in the CovR/CovS regulatory system are more invasive and related to severe manifestations. GAS can replicate inside phagocytic cells; therefore, phagocytic cells could serve as the niche to select invasive covS mutants. Nonetheless, the encapsula...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Chiang-Ni, Chuan, Shi, Yong-An, Lai, Chih-Ho, Chiu, Cheng-Hsun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218877/
https://ncbi.nlm.nih.gov/pubmed/30425702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02592
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