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Effect of Phosphatase Activity of the Control of Virulence Sensor (CovS) on Clindamycin-Mediated Streptolysin O Production in Group A Streptococcus

Severe manifestations of group A Streptococcus (GAS) infections are associated with massive tissue destruction and high mortality. Clindamycin (CLI), a bacterial protein synthesis inhibitor, is recommended for treating patients with severe invasive GAS infection. Nonetheless, the subinhibitory conce...

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Publicado en:Infect Immun
Main Authors: Chiang-Ni, Chuan, Tseng, Huei-Chuan, Shi, Yong-An, Chiu, Cheng-Hsun
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867833/
https://ncbi.nlm.nih.gov/pubmed/31527126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00583-19
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