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Clindamycin-Induced CovS-Mediated Regulation of the Production of Virulent Exoproteins Streptolysin O, NAD Glycohydrolase, and Streptokinase in Streptococcus pyogenes

The administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome. However, the prevalence of CLI-resistant Streptococcus pyogenes strains is increasing worldwide, and the effect of CLI on CLI-resistant S. pyogenes strains...

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Detalhes bibliográficos
Main Authors: Minami, Masaaki, Kamimura, Takuya, Isaka, Masanori, Tatsuno, Ichiro, Ohta, Michio, Hasegawa, Tadao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798487/
https://ncbi.nlm.nih.gov/pubmed/19805566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00804-09
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