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RAC1 as a Therapeutic Target in Malignant Melanoma

Small GTPases of the RAS and RHO families are related signaling proteins that, when activated by growth factors or by mutation, drive oncogenic processes. While activating mutations in KRAS, NRAS, and HRAS genes have long been recognized and occur in many kinds of cancers, similar mutations in RHO f...

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Bibliografische gegevens
Gepubliceerd in:Trends Cancer
Hoofdauteurs: Cannon, Alexa, Alvarez, Cristina Uribe, Chernoff, Jonathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380552/
https://ncbi.nlm.nih.gov/pubmed/32460002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.02.021
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