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RAC1 as a Therapeutic Target in Malignant Melanoma

Small GTPases of the RAS and RHO families are related signaling proteins that, when activated by growth factors or by mutation, drive oncogenic processes. While activating mutations in KRAS, NRAS, and HRAS genes have long been recognized and occur in many kinds of cancers, similar mutations in RHO f...

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Detalhes bibliográficos
Publicado no:Trends Cancer
Main Authors: Cannon, Alexa, Alvarez, Cristina Uribe, Chernoff, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380552/
https://ncbi.nlm.nih.gov/pubmed/32460002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.02.021
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