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RAC1 and Melanoma

The mutant RAC1(P29S), a GTPase member of the RAS superfamily, was identified as the third most common recurrent mutation in melanomas. There is limited information regarding the functional role of RAC1(P29S) as a “driver” in melanogenesis and as a cause for drug resistance. This commentary describe...

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Detalhes bibliográficos
Publicado no:Clin Ther
Autor principal: Halaban, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415501/
https://ncbi.nlm.nih.gov/pubmed/25465943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinthera.2014.10.027
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