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RAC1 and Melanoma
The mutant RAC1(P29S), a GTPase member of the RAS superfamily, was identified as the third most common recurrent mutation in melanomas. There is limited information regarding the functional role of RAC1(P29S) as a “driver” in melanogenesis and as a cause for drug resistance. This commentary describe...
Enregistré dans:
| Publié dans: | Clin Ther |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4415501/ https://ncbi.nlm.nih.gov/pubmed/25465943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinthera.2014.10.027 |
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