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Targeting effector pathways in RAC1(P29S)-driven malignant melanoma
Malignant melanoma is characterized by mutations in a number of driver genes, most notably BRAF and NRAS. Recent genomic analyses revealed that 4-9% of sun-exposed melanomas bear activating mutations in RAC1, which encodes a small GTPase that is known to play key roles in cell proliferation, surviva...
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| Publicado no: | Small GTPases |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205048/ https://ncbi.nlm.nih.gov/pubmed/32043900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2020.1728469 |
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