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The magnesium transporter NIPAL1 is a pancreatic islet–expressed protein that conditionally impacts insulin secretion
Type 2 diabetes is a chronic metabolic disease characterized by pancreatic β-cell dysfunction and peripheral insulin resistance. Among individuals with type 2 diabetes, ∼30% exhibit hypomagnesemia. Hypomagnesemia has been linked to insulin resistance through reduced tyrosine kinase activity of the i...
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| Vydáno v: | J Biol Chem |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380176/ https://ncbi.nlm.nih.gov/pubmed/32439805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013277 |
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