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The effect of unhealthy β-cells on insulin secretion in pancreatic islets

BACKGROUND: Insulin secreted by pancreatic islet β-cells is the principal regulating hormone of glucose metabolism and plays a key role in controlling glucose level in blood. Impairment of the pancreatic islet function may cause glucose to accumulate in blood, and result in diabetes mellitus. Recent...

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Detalhes bibliográficos
Main Authors: Pu, Yang, Lee, Saangho, Samuels, David C, Watson, Layne T, Cao, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981690/
https://ncbi.nlm.nih.gov/pubmed/24565418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-S3-S6
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