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Overexpression of Pref-1 in pancreatic islet β-cells in mice causes hyperinsulinemia with increased Islet Mass and insulin secretion
Preadipocyte factor-1 (Pref-1) is made as a transmembrane protein containing EGF-repeats at the extracellular domain that can be cleaved to generate a biologically active soluble form. Pref-1 is found in islet β-cells and its level has been reported to increase in neonatal rat islets upon growth hor...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439292/ https://ncbi.nlm.nih.gov/pubmed/25918019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.04.078 |
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