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The magnesium transporter NIPAL1 is a pancreatic islet–expressed protein that conditionally impacts insulin secretion

Type 2 diabetes is a chronic metabolic disease characterized by pancreatic β-cell dysfunction and peripheral insulin resistance. Among individuals with type 2 diabetes, ∼30% exhibit hypomagnesemia. Hypomagnesemia has been linked to insulin resistance through reduced tyrosine kinase activity of the i...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Manialawy, Yousef, Khan, Saifur R., Bhattacharjee, Alpana, Wheeler, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380176/
https://ncbi.nlm.nih.gov/pubmed/32439805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013277
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