Propeptide glycosylation and galectin‐3 binding decrease proteolytic activation of human proMMP‐9/progelatinase B

Matrix metalloproteinases (MMPs) are secreted as proenzymes, containing propeptides that interact with the catalytic zinc, thereby controlling MMP activation. The MMP‐9 propeptide is unique in the MMP family because of its post‐translational modification with an N‐linked oligosaccharide. ProMMP‐9 ac...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:FEBS J
Päätekijät: Boon, Lise, Ugarte‐Berzal, Estefania, Martens, Erik, Vandooren, Jennifer, Rybakin, Vasily, Colau, Didier, Gordon‐Alonso, Monica, van der Bruggen, Pierre, Stöcker, Walter, Becker‐Pauly, Christoph, Witters, Peter, Morava, Eva, Jaeken, Jaak, Proost, Paul, Opdenakker, Ghislain
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379967/
https://ncbi.nlm.nih.gov/pubmed/30422384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14698
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