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Photodynamic exposure of Rose-Bengal inhibits Tau aggregation and modulates cytoskeletal network in neuronal cells

The intracellular Tau aggregates are known to be associated with Alzheimer’s disease. The inhibition of Tau aggregation is an important strategy for screening of therapeutic molecules in Alzheimer's disease. Several classes of dyes possess a unique property of photo-excitation, which is applied...

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書目詳細資料
發表在:Sci Rep
Main Authors: Dubey, Tushar, Gorantla, Nalini Vijay, Chandrashekara, Kagepura Thammaiah, Chinnathambi, Subashchandrabose
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378248/
https://ncbi.nlm.nih.gov/pubmed/32704015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69403-2
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