Neem Derivatives Inhibits Tau Aggregation(1)

Tau is a phosphoprotein with natively unfolded conformation that functions to stabilize microtubules in axons. Alzheimer’s disease pathology triggers several modifications in tau, which causes it to lose its affinity towards microtubule, thus, leading to microtubule disassembly and loss of axonal in...

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Библиографические подробности
Опубликовано в: :J Alzheimers Dis Rep
Главные авторы: Gorantla, Nalini V., Das, Rashmi, Mulani, Fayaj A., Thulasiram, Hirekodathakallu V., Chinnathambi, Subashchandrabose
Формат: Artigo
Язык:Inglês
Опубликовано: IOS Press 2019
Предметы:
Research Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597962/
https://ncbi.nlm.nih.gov/pubmed/31259310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-190118
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