Neem Derivatives Inhibits Tau Aggregation(1)

Tau is a phosphoprotein with natively unfolded conformation that functions to stabilize microtubules in axons. Alzheimer’s disease pathology triggers several modifications in tau, which causes it to lose its affinity towards microtubule, thus, leading to microtubule disassembly and loss of axonal in...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis Rep
Main Authors: Gorantla, Nalini V., Das, Rashmi, Mulani, Fayaj A., Thulasiram, Hirekodathakallu V., Chinnathambi, Subashchandrabose
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2019
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597962/
https://ncbi.nlm.nih.gov/pubmed/31259310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-190118
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