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Photodynamic exposure of Rose-Bengal inhibits Tau aggregation and modulates cytoskeletal network in neuronal cells

The intracellular Tau aggregates are known to be associated with Alzheimer’s disease. The inhibition of Tau aggregation is an important strategy for screening of therapeutic molecules in Alzheimer's disease. Several classes of dyes possess a unique property of photo-excitation, which is applied...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dubey, Tushar, Gorantla, Nalini Vijay, Chandrashekara, Kagepura Thammaiah, Chinnathambi, Subashchandrabose
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378248/
https://ncbi.nlm.nih.gov/pubmed/32704015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69403-2
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