EGCG impedes human Tau aggregation and interacts with Tau

Tau aggregation and accumulation is a key event in the pathogenesis of Alzheimer’s disease. Inhibition of Tau aggregation is therefore a potential therapeutic strategy to ameliorate the disease. Phytochemicals are being highlighted as potential aggregation inhibitors. Epigallocatechin-3-gallate (EGC...

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Vydáno v:Sci Rep
Hlavní autoři: Sonawane, Shweta Kishor, Chidambaram, Hariharakrishnan, Boral, Debjyoti, Gorantla, Nalini Vijay, Balmik, Abhishek Ankur, Dangi, Abha, Ramasamy, Sureshkumar, Marelli, Udaya Kiran, Chinnathambi, Subashchandrabose
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387440/
https://ncbi.nlm.nih.gov/pubmed/32724104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69429-6
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