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The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau
BACKGROUND: Microtubule-associated protein Tau undergoes aggregation in Alzheimer`s disease (AD) and a group of other related diseases collectively known as Tauopathies. In AD, Tau forms aggregates, which are deposited intracellularly as neurofibrillary tangles. Histone deacetylase-6 (HDAC6) plays a...
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| Publicado en: | Cell Commun Signal |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8088071/ https://ncbi.nlm.nih.gov/pubmed/33933071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-021-00736-9 |
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