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Pyridoxal-5′-Phosphate-Dependent Alkyl Transfer in Nucleoside Antibiotic Biosynthesis
Several nucleoside antibiotics are structurally characterized by a 5′′-amino-5′′-deoxyribose (ADR) appended via a glycosidic bond to a high-carbon sugar nucleoside, (5′S,6′S)-5′-C-glycyluridine (GlyU). GlyU is further modified with an N-alkylamine linker, the biosynthetic origins of which have yet t...
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| 出版年: | Nat Chem Biol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7377962/ https://ncbi.nlm.nih.gov/pubmed/32483377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0548-3 |
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