Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics

Muraymycins belong to a family of nucleoside antibiotics that have a distinctive disaccharide core consisting of 5-amino-5-deoxyribofuranose (ADR) attached to 6′-N-alkyl-5′-C-glycyluridine (GlyU). Here we functionally assign and characterize six enzymes from the muraymycin biosynthetic pathway invol...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Cui, Zheng, Liu, Xiaodong, Overbay, Jonathan, Cai, Wenlong, Wang, Xiachang, Lemke, Anke, Wiegmann, Daniel, Niro, Giuliana, Thorson, Jon S., Ducho, Christian, Van Lanen, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291243/
https://ncbi.nlm.nih.gov/pubmed/29768920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b00855
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