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Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit

Muraymycins are a subclass of naturally occurring nucleoside antibiotics with promising antibacterial activity. They inhibit the bacterial enzyme translocase I (MraY), a clinically yet unexploited target mediating an essential intracellular step of bacterial peptidoglycan biosynthesis. Several struc...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Heib, Anna, Niro, Giuliana, Weck, Stefanie C., Koppermann, Stefan, Ducho, Christian
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983020/
https://ncbi.nlm.nih.gov/pubmed/31861655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010022
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