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Muraymycin nucleoside-peptide antibiotics: uridine-derived natural products as lead structures for the development of novel antibacterial agents

Muraymycins are a promising class of antimicrobial natural products. These uridine-derived nucleoside-peptide antibiotics inhibit the bacterial membrane protein translocase I (MraY), a key enzyme in the intracellular part of peptidoglycan biosynthesis. This review describes the structures of natural...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Wiegmann, Daniel, Koppermann, Stefan, Wirth, Marius, Niro, Giuliana, Leyerer, Kristin, Ducho, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902027/
https://ncbi.nlm.nih.gov/pubmed/27340469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.77
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