The up‐regulation of NDRG1 by HIF counteracts the cancer‐promoting effect of HIF in VHL‐deficient clear cell renal cell carcinoma

BACKGROUND: Hypoxia‐inducible factors (HIFs) are thought to play important roles in the carcinogenesis and progression of VHL‐deficient clear cell renal cell carcinoma (ccRCC). METHODS: The roles of HIF‐1/2α in VHL‐deficient clear cell renal cell carcinoma were evaluated by bioinformatics analysis,...

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Publicat a:Cell Prolif
Autors principals: Zhang, Zheng‐Yan, Zhang, Shi‐Long, Chen, Hui‐Ling, Mao, Yu‐Qin, Li, Zhan‐Ming, Kong, Chao‐Yue, Han, Bing, Zhang, Jin, Chen, Yong‐Hui, Xue, Wei, Zhai, Wei, Wang, Li‐Shun
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377940/
https://ncbi.nlm.nih.gov/pubmed/32537867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12853
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