Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α

Both the von Hippel-Lindau (VHL)/hypoxia-inducible factor (HIF) pathway and microRNA (miRNA) regulation are important mechanisms underlying the development and progression of clear cell renal cell carcinoma (ccRCC). Here we demonstrate that VHL deficiency leads to downregulation of Dicer and, in tur...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Fan, Yang, Li, Hongzhao, Ma, Xin, Gao, Yu, Bao, Xu, Du, Qingshan, Ma, Minghui, Liu, Kan, Yao, Yuanxin, Huang, Qingbo, Zhang, Yu, Zhang, Xu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951288/
https://ncbi.nlm.nih.gov/pubmed/26943772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7807
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