E2F3 upregulation promotes tumor malignancy through the transcriptional activation of HIF-2α in clear cell renal cell carcinoma

The E2F3 transcriptional regulatory pathway plays a major part in multiple-cancer progression, but the specific contributions of this pathway to tumor formation and the progression of clear cell renal cell carcinoma (ccRCC) are not fully understood. Clinically, we demonstrated that E2F3 was overexpr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gao, Yu, Li, Hongzhao, Ma, Xin, Fan, Yang, Ni, Dong, Zhang, Yu, Huang, Qingbo, Liu, Kan, Li, Xintao, Wang, Lei, Yao, Yuanxin, Ai, Qing, Zhang, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589559/
https://ncbi.nlm.nih.gov/pubmed/28903320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10568
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