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Tracking RNA with light: selection, structure, and design of fluorescence turn-on RNA aptamers

Fluorescence turn-on aptamers, in vitro evolved RNA molecules that bind conditional fluorophores and activate their fluorescence, have emerged as RNA counterparts of the fluorescent proteins. Turn-on aptamers have been selected to bind diverse fluorophores, and they achieve varying degrees of specif...

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Detalles Bibliográficos
Publicado en:Q Rev Biophys
Main Authors: Trachman, Robert J., Ferré-D’Amaré, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377909/
https://ncbi.nlm.nih.gov/pubmed/31423956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583519000064
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