Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage

Phthiocerol dimycocerosates (PDIMs) are a class of mycobacterial lipids that promote virulence in Mycobacterium tuberculosis and Mycobacterium marinum. It has recently been shown that PDIMs work in concert with the M. tuberculosis Type VII secretion system ESX-1 to permeabilize the phagosomal membra...

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Publicado en:PLoS One
Main Authors: Osman, Morwan M., Pagán, Antonio J., Shanahan, Jonathan K., Ramakrishnan, Lalita
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377490/
https://ncbi.nlm.nih.gov/pubmed/32701962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233252
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