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Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage

Phthiocerol dimycocerosates (PDIMs) are a class of mycobacterial lipids that promote virulence in Mycobacterium tuberculosis and Mycobacterium marinum. It has recently been shown that PDIMs work in concert with the M. tuberculosis Type VII secretion system ESX-1 to permeabilize the phagosomal membra...

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Publié dans:PLoS One
Auteurs principaux: Osman, Morwan M., Pagán, Antonio J., Shanahan, Jonathan K., Ramakrishnan, Lalita
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377490/
https://ncbi.nlm.nih.gov/pubmed/32701962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233252
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