Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

Phthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium tuberculosis (Mtb), in particular during the early step of infection when bacilli encounter their host macrophages. However, their cellular and molecular mechanisms of action remain unknown. Using Mtb mutants deleted for...

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Main Authors: Astarie-Dequeker, Catherine, Le Guyader, Laurent, Malaga, Wladimir, Seaphanh, Fam-Ky, Chalut, Christian, Lopez, André, Guilhot, Christophe
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632888/
https://ncbi.nlm.nih.gov/pubmed/19197369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000289
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