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Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

Phthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium tuberculosis (Mtb), in particular during the early step of infection when bacilli encounter their host macrophages. However, their cellular and molecular mechanisms of action remain unknown. Using Mtb mutants deleted for...

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Main Authors: Astarie-Dequeker, Catherine, Le Guyader, Laurent, Malaga, Wladimir, Seaphanh, Fam-Ky, Chalut, Christian, Lopez, André, Guilhot, Christophe
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2009
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632888/
https://ncbi.nlm.nih.gov/pubmed/19197369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000289
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