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Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

Phthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium tuberculosis (Mtb), in particular during the early step of infection when bacilli encounter their host macrophages. However, their cellular and molecular mechanisms of action remain unknown. Using Mtb mutants deleted for...

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Autors principals: Astarie-Dequeker, Catherine, Le Guyader, Laurent, Malaga, Wladimir, Seaphanh, Fam-Ky, Chalut, Christian, Lopez, André, Guilhot, Christophe
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632888/
https://ncbi.nlm.nih.gov/pubmed/19197369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000289
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