Identification of the Missing trans-Acting Enoyl Reductase Required for Phthiocerol Dimycocerosate and Phenolglycolipid Biosynthesis in Mycobacterium tuberculosis

Phthiocerol dimycocerosates (DIM) and phenolglycolipids (PGL) are functionally important surface-exposed lipids of Mycobacterium tuberculosis. Their biosynthesis involves the products of several genes clustered in a 70-kb region of the M. tuberculosis chromosome. Among these products is PpsD, one of...

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Bibliographic Details
Main Authors: Siméone, Roxane, Constant, Patricia, Guilhot, Christophe, Daffé, Mamadou, Chalut, Christian
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Molecular Biology of Pathogens
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913427/
https://ncbi.nlm.nih.gov/pubmed/17468241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00169-07
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