Rutaecarpine inhibits KEAP1-NRF2 interaction to activate NRF2 and ameliorate dextran sulfate sodium-induced colitis

Inflammatory bowel disease (IBD) represents a group of chronic relapsing intestinal disorders. Rutaecarpine (RUT), isolated from the Traditional Chinese Medicine (TCM) of Evodia rutaecarpa, was reported to suppress IBD. However, the mechanism by which RUT ameliorates dextran sulfate sodium (DSS)-ind...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Free Radic Biol Med
Hlavní autoři: Zhang, Youbo, Yan, Tingting, Sun, Dongxue, Xie, Cen, Wang, Tianxia, Liu, Xiaoyan, Wang, Jing, Wang, Qiong, Luo, Yuhong, Wang, Ping, Yagai, Tomoki, Krausz, Kristopher W., Yang, Xiuwei, Gonzalez, Frank J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376370/
https://ncbi.nlm.nih.gov/pubmed/31874248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.12.012
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky