Structure-Activity Relationships of the Main Bioactive Constituents of Euodia rutaecarpa on Aryl Hydrocarbon Receptor Activation and Associated Bile Acid Homeostasis

Rutaecarpine (RUT), evodiamine (EOD), and dehydroevodiamine (DHED) are the three main bioactive indoloquinazoline alkaloids isolated from Euodia rutaecarpa, a widely prescribed traditional Chinese medicine. Here, the structure-activity relationships of these analogs for aryl hydrocarbon receptor (AH...

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Bibliografski detalji
Izdano u:Drug Metab Dispos
Glavni autori: Zhang, Youbo, Yan, Tingting, Sun, Dongxue, Xie, Cen, Zheng, Yiran, Zhang, Lei, Yagai, Tomoki, Krausz, Kristopher W., Bisson, William H., Yang, Xiuwei, Gonzalez, Frank J.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2018
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003592/
https://ncbi.nlm.nih.gov/pubmed/29691238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.080176
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