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Structure-Activity Relationships of the Main Bioactive Constituents of Euodia rutaecarpa on Aryl Hydrocarbon Receptor Activation and Associated Bile Acid Homeostasis

Rutaecarpine (RUT), evodiamine (EOD), and dehydroevodiamine (DHED) are the three main bioactive indoloquinazoline alkaloids isolated from Euodia rutaecarpa, a widely prescribed traditional Chinese medicine. Here, the structure-activity relationships of these analogs for aryl hydrocarbon receptor (AH...

詳細記述

保存先:
書誌詳細
出版年:Drug Metab Dispos
主要な著者: Zhang, Youbo, Yan, Tingting, Sun, Dongxue, Xie, Cen, Zheng, Yiran, Zhang, Lei, Yagai, Tomoki, Krausz, Kristopher W., Bisson, William H., Yang, Xiuwei, Gonzalez, Frank J.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003592/
https://ncbi.nlm.nih.gov/pubmed/29691238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.080176
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