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Observing Protein Degradation by the PAN-20S Proteasome by Time-Resolved Neutron Scattering

The proteasome is a key player of regulated protein degradation in all kingdoms of life. Although recent atomic structures have provided snapshots on a number of conformations, data on substrate states and populations during the active degradation process in solution remain scarce. Here, we use time...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Mahieu, Emilie, Covès, Jacques, Krüger, Georg, Martel, Anne, Moulin, Martine, Carl, Nico, Härtlein, Michael, Carlomagno, Teresa, Franzetti, Bruno, Gabel, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376118/
https://ncbi.nlm.nih.gov/pubmed/32640186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.015
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