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Small-angle neutron scattering reveals the assembly mode and oligomeric architecture of TET, a large, dodecameric aminopeptidase

The specific self-association of proteins into oligomeric complexes is a common phenomenon in biological systems to optimize and regulate their function. However, de novo structure determination of these important complexes is often very challenging for atomic-resolution techniques. Furthermore, in...

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Publicat a:Acta Crystallogr D Biol Crystallogr
Autors principals: Appolaire, Alexandre, Girard, Eric, Colombo, Matteo, Durá, M. Asunción, Moulin, Martine, Härtlein, Michael, Franzetti, Bruno, Gabel, Frank
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220976/
https://ncbi.nlm.nih.gov/pubmed/25372688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714018446
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