Pyrococcus horikoshii TET2 Peptidase Assembling Process and Associated Functional Regulation

Tetrahedral (TET) aminopeptidases are large polypeptide destruction machines present in prokaryotes and eukaryotes. Here, the rules governing their assembly into hollow 12-subunit tetrahedrons are addressed by using TET2 from Pyrococcus horikoshii (PhTET2) as a model. Point mutations allowed the cap...

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Detalhes bibliográficos
Main Authors: Appolaire, Alexandre, Rosenbaum, Eva, Durá, M. Asunción, Colombo, Matteo, Marty, Vincent, Savoye, Marjolaine Noirclerc, Godfroy, Anne, Schoehn, Guy, Girard, Eric, Gabel, Frank, Franzetti, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829341/
https://ncbi.nlm.nih.gov/pubmed/23696647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450189
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