SAXS/SANS on Supercharged Proteins Reveals Residue-Specific Modifications of the Hydration Shell

Water molecules in the immediate vicinity of biomacromolecules, including proteins, constitute a hydration layer characterized by physicochemical properties different from those of bulk water and play a vital role in the activity and stability of these structures, as well as in intermolecular intera...

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Publicat a:Biophys J
Autors principals: Kim, Henry S., Martel, Anne, Girard, Eric, Moulin, Martine, Härtlein, Michael, Madern, Dominique, Blackledge, Martin, Franzetti, Bruno, Gabel, Frank
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2016
Matèries:
Proteins
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880798/
https://ncbi.nlm.nih.gov/pubmed/27224484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.013
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