Role of Ca(2+) transients at the node of the mouse embryo in breaking of left-right symmetry

Immotile cilia sense extracellular signals such as fluid flow, but whether Ca(2+) plays a role in flow sensing has been unclear. Here, we examined the role of ciliary Ca(2+) in the flow sensing that initiates the breaking of left-right (L-R) symmetry in the mouse embryo. Intraciliary and cytoplasmic...

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Udgivet i:Sci Adv
Main Authors: Mizuno, Katsutoshi, Shiozawa, Kei, Katoh, Takanobu A., Minegishi, Katsura, Ide, Takahiro, Ikawa, Yayoi, Nishimura, Hiromi, Takaoka, Katsuyoshi, Itabashi, Takeshi, Iwane, Atsuko H., Nakai, Junichi, Shiratori, Hidetaka, Hamada, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375832/
https://ncbi.nlm.nih.gov/pubmed/32743070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba1195
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