CD11a expression distinguishes infiltrating myeloid cells from plaque-associated microglia in Alzheimer’s Disease.

Alzheimer’s Disease (AD) is the leading cause of age-related neurodegeneration and is characterized neuropathologically by the accumulation of insoluble beta-amyloid (Aß) peptides. In AD brains, plaque-associated myeloid (PAM) cells cluster around Aß plaques but fail to effectively clear Aß by phago...

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Veröffentlicht in:Glia
Hauptverfasser: Shukla, Ankita K., McIntyre, Laura L., Marsh, Samuel E., Schneider, Christine A., Hoover, Evelyn M., Walsh, Craig T., Lodoen, Melissa B., Blurton-Jones, Mathew, Inlay, Matthew A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375697/
https://ncbi.nlm.nih.gov/pubmed/30588668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23575
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