Human Helicase DDX: Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation (Adv. Sci. 14/2020)

In article number 2000532, Jixi Li and co‐workers report a set of four crystal structures of human RNA helicase DDX21, revealing dramatic conformational rearrangements during the RNA unwinding cycle. Furthermore, the discovery of small RNAs modulating the interaction between DDX21 and viral protein...

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Vydáno v:Adv Sci (Weinh)
Hlavní autoři: Chen, Zijun, Li, Zhengyang, Hu, Xiaojian, Xie, Feiyan, Kuang, Siyun, Zhan, Bowen, Gao, Wenqing, Chen, Xiangjun, Gao, Siqi, Li, Yang, Wang, Yongming, Qian, Feng, Ding, Chen, Gan, Jianhua, Ji, Chaoneng, Xu, Xue‐Wei, Zhou, Zheng, Huang, Jinqing, He, Housheng Hansen, Li, Jixi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375237/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202070077
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